N=E1
“anyone” · runs an n‑of‑1

Evidence used to belong to institutions. Now it belongs to everyone.

NE1 turns self-experimentation into real science — structured N-of-1 trials, group studies, and clinician-run protocols that pool into open, population-scale evidence. A full pipeline from a hunch to published proof.

SCROLL
Three ways in

One platform. Every scale of science.

Whether you're an individual chasing an answer for your own body, a community pooling a cohort, or a clinician guiding patients — the same rigorous machinery is behind you.

01

Run a solo N-of-1

Design or pick a protocol, log outcomes daily, and get a real statistical readout — Cohen's d, Bayesian effect estimates, the works — on whether it actually worked for you.

For self-experimenters
02

Launch a group study

Rally a cohort around a single question. Standardized protocols turn scattered anecdotes into a dataset with real statistical power — forest plots, response rates, and all.

For communities
03

Manage your patients

Prescribe protocols, monitor compliance and outcomes in real time, and contribute clinician-grade observations that carry more evidentiary weight than self-reports.

For clinicians
The bigger picture

A clinical answer takes a decade and tens of millions of dollars. It shouldn't.

Today, the questions that actually matter to people — does this peptide help my tendon heal, does this compound sharpen focus, does this protocol extend healthspan — sit unanswered. The traditional trial pipeline is too slow, too expensive, and too narrow to reach them.

Meanwhile, millions are already experimenting on themselves. They're generating real data every single day — and it vanishes into forums, group chats, and DMs, never to be measured, compared, or learned from.

NE1 captures that energy and gives it structure. Rigorous protocols, honest statistics, transparent prediction markets, and community-funded trials — a continuous loop that turns lived experience into evidence the whole world can use.

This is science as an open commons. Not gatekept. Not buried in a paywalled journal three years too late. Built, run, and owned by the community asking the questions.

N=1
Every individual is a study
N=∞
Pooled into population evidence
0→1
From hunch to published proof
The loop

How a question becomes evidence.

01 / DISCOVER

Explore the library

Dive into the deepest molecule registry anywhere — mechanisms, research, and real-world signal, all tiered by evidence strength.

02 / RUN

Run structured studies

Enroll in a protocol or build your own. Track outcomes daily and get a statistically honest read on what happened.

03 / PREDICT

Predict outcomes

Stake your conviction in prediction markets. Crowd belief surfaces the questions most worth answering for real.

04 / FUND

Fund real trials

When a signal is strong enough, the community funds a formal study — and the results flow right back into the library.

The molecule library

The compounds people are actually researching.

From regenerative peptides to longevity small molecules — each with a living evidence file that grows every time someone runs a study.

Be first in

Help build the open future of medicine.

We're onboarding the founding cohort of researchers, clinicians, and self-experimenters. Add your name and we'll reach out as we open the doors.

You're on the list.

Welcome to the founding cohort. We'll be in touch soon.